There are 21 incorporated places in the Region. Between 2000 and 2015 the population in incorporated places grew 6.7%, adding 3,248 persons. Only six of the 21 places lost population. More growth occurred in the unincorporated area of the Region than in incorporated places. The four largest cities are clustered along the US-67 corridor in St. Francois County creating an urbanized area with over 30,000 residents. The Region also has several Census Designated Places which are like large rural subdivisions; they are often managed by property owners associations. Terre du Lac with a population of 2,418 is the largest. It is unusual to find this type of development in rural Missouri.